گروه پزشکی مولکولی

زمینه های تحقیقاتی

اولویت های  تحقیقاتی گروه:

  • درمان و شناخت سرطان
  • بیومارکرها و تشخیص بیماریها
  • مطالعات سلولهای بنیادی

 مقالات اخیرا منتشر شده:

Dr. M.H. Ghahremani

1: Montazeri H, Bouzari S, Azadmanesh K, Ostad SN, Ghahremani MH. Divergent behavior of cyclin E and its low molecular weight isoforms to progesterone-induced growth inhibition in MCF-7 cells. Adv Biomed Res. 2015 Jan 6;4:16.

2: Payan M, Rouini MR, Tajik N, Ghahremani MH, Tahvilian R. Hydroxylation index of omeprazole in relation to CYP2C19 polymorphism and sex in a healthy Iranian population. Daru. 2014 Dec 11;22(1):81.

3: Ghods R, Ghahremani MH, Madjd Z, Asgari M, Abolhasani M, Tavasoli S, Mahmoudi AR, Darzi M, Pasalar P, Jeddi-Tehrani M, Zarnani AH. High placenta-specific 1/low prostate-specific antigen expression pattern in high-grade prostate adenocarcinoma. Cancer Immunol Immunother. 2014 Dec;63(12):1319-27.

4: Paknejad B, Kebriaeezadeh A, Ghahremani MH, Gharghabi M, Ostad SN. Gabapentin Enhances Neurogenesis in E14 Rat Embryonic Neocortex Stem Cells. Drug Res (Stuttg). 2014 Jul 30. [Epub ahead of print]

5: Akbari A, Amanpour S, Muhammadnejad S, Ghahremani MH, Ghaffari SH, Dehpour AR, Mobini GR, Shidfar F, Abastabar M, Khoshzaban A, Faghihloo E, Karimi A, Heidari M. Evaluation of antitumor activity of a TGF-beta receptor I inhibitor (SD-208) on human colon adenocarcinoma. Daru. 2014 Jun 5;22:47.

6: Sepehri N, Rouhani H, Ghanbarpour AR, Gharghabi M, Tavassolian F, Amini M, Ostad SN, Ghahremani MH, Dinarvand R. Human serum albumin conjugates of 7-ethyl-10-hydroxycamptothecin (SN38) for cancer treatment. Biomed Res Int. 2014;2014:963507.

7: Goodarzi N, Ghahremani MH, Amini M, Atyabi F, Ostad SN, Shabani Ravari N, Nateghian N, Dinarvand R. CD44-targeted docetaxel conjugate for cancer cells and cancer stem-like cells: a novel hyaluronic acid-based drug delivery system. Chem Biol Drug Des. 2014 Jun;83(6):741-52.

8: Mandegary A, Torshabi M, Seyedabadi M, Amirheidari B, Sharif E, Ghahremani MH. Indomethacin-enhanced anticancer effect of arsenic trioxide in A549 cell line: involvement of apoptosis and phospho-ERK and p38 MAPK pathways. Biomed Res Int. 2013;2013:237543.

Dr. G. Tavoosidana

1: Mirzaei A, Tavoosidana G, Modarressi MH, Rad AA, Fazeli MS, Shirkoohi R,Tavakoli-Yaraki M, Madjd Z. Upregulation of circulating cancer stem cell marker, DCLK1 but not Lgr5, in chemoradiotherapy-treated colorectal cancer patients. Tumour Biol. 2015 Jan 29. [Epub ahead of print]

2: Hamidi SV, Ghourchian H, Tavoosidana G. Real-time detection of H(5)N(1) influenza virus through hyperbranched rolling circle amplification. Analyst. 2015 Jan 28. [Epub ahead of print]

3: Nazeri N, Avadi MR, Faramarzi MA, Safarian S, Tavoosidana G, Khoshayand MR, Amani A. Effect of preparation parameters on ultra low molecular weight chitosan/hyaluronic acid nanoparticles. Int J Biol Macromol. 2013 Nov;62:642-6.

4: Saber R, Shakoori Z, Sarkar S, Tavoosidana G, Kharrazi S, Gill P.Spectroscopic and microscopic analyses of rod-shaped gold nanoparticles interacting with single-stranded DNA oligonucleotides. IET Nanobiotechnol. 2013 Jun;7(2):42-9.

5: Tavoosidana G, Ronquist G, Darmanis S, Yan J, Carlsson L, Wu D, Conze T, Ek P, Semjonow A, Eltze E, Larsson A, Landegren UD, Kamali-Moghaddam M. Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer. Proc Natl Acad Sci U S A. 2011 May 24.

Dr. A. Golestani

Dr. M.H. Modaressi

Dr. E. Motevaseli

Dr. B. Nikbin

1: Roohi A, Tabrizi M, Abbasi F, Ataie-Jafari A, Nikbin B, Larijani B, Qorbani M, Meysamie A, Asgarian-Omran H, Nikmanesh B, Bajouri A, Shafiey N, Maleki A. Serum  IL-17, IL-23, and TGF-β levels in type 1 and type 2 diabetic patients and age-matched healthy controls. Biomed Res Int. 2014;2014:718946.

2: Shakiba Y, Koopah S, Jamshidi AR, Amirzargar AA, Massoud A, Kiani A, Nicknam MH, Nazari B, Nikbin B. Anti-cyclic citrullinated peptide antibody and rheumatoid factor isotypes in Iranian patients with rheumatoid arthritis: evaluation of clinical value and association with disease activity. Iran J Allergy Asthma Immunol. 2014 Jun;13(3):147-56.

3: Ardalan M, Ghafari A, Hamzavi F, Nasri H, Baradaran B, Majidi J, Nikbin B. Anti-phospholipase A2 receptor antibody in idiopathic membranous nephropathy: A report from Iranian population. J Nephropathol. 2013 Oct;2(4):241-8.

4: Arshadi D, Nikbin B, Shakiba Y, Kiani A, Jamshidi AR, Boroushaki MT. Plasma level of neopterin as a marker of disease activity in treated rheumatoid arthritis patients: association with gender, disease activity and anti-CCP antibody. Int Immunopharmacol. 2013 Nov;17(3):763-7.

5: Nazari B, Amirzargar A, Nikbin B, Nafar M, Ahmadpour P, Einollahi B, Lesan Pezeshki M, Khatami SM, Ansaripour B, Nikuinejad H, Mohamadi F, Mahmoudi M, Soltani S, Nicknam MH. Comparison of the Th1, IFN-γ secreting cells and FoxP3 expression between patients with stable graft function and acute rejection post kidney transplantation. Iran J Allergy Asthma Immunol. 2013 Jul 13;12(3):262-8.

6: Davatchi F, Nikbin B, Shams H, Sadeghi Abdollahi B, Mohyeddin M, Shahram F. Mesenchymal stem cell therapy unable to rescue the vision from advanced Behcet's  disease retinal vasculitis: report of three patients. Int J Rheum Dis. 2013 Apr;16(2):139-47.

Dr. P. Pasalar

1: Hashemi R, Motlagh AD, Heshmat R, Esmaillzadeh A, Payab M, Yousefinia M, Siassi F, Pasalar P, Baygi F. Diet and its relationship to sarcopenia in community dwelling Iranian elderly: a cross sectional study. Nutrition. 2015 Jan;31(1):97-104.

2: Ghods R, Ghahremani MH, Madjd Z, Asgari M, Abolhasani M, Tavasoli S, Mahmoudi  AR, Darzi M, Pasalar P, Jeddi-Tehrani M, Zarnani AH. High placenta-specific 1/low prostate-specific antigen expression pattern in high-grade prostate adenocarcinoma. Cancer Immunol Immunother. 2014 Dec;63(12):1319-27.

3: Maghbooli Z, Hossein-Nezhad A, Larijani B, Pasalar P, Keshtkar AA. Association between alterations in global DNA methylation and predisposing factors in diabetes: a high pressure liquid chromatography based study. Minerva Med. 2014 Jul 31. [Epub ahead of print]

4: Sabetkish S, Kajbafzadeh AM, Sabetkish N, Khorramirouz R, Akbarzadeh A, Seyedian SL, Pasalar P, Orangian S, Beigi RS, Aryan Z, Akbari H, Tavangar SM. Whole-organ tissue engineering: Decellularization and recellularization of three-dimensional matrix liver scaffolds. J Biomed Mater Res A. 2014 Jul 21.

5: Maghbooli Z, Larijani B, Emamgholipour S, Amini M, Keshtkar A, Pasalar P. Aberrant DNA methylation patterns in diabetic nephropathy. J Diabetes Metab Disord. 2014 Jun 24;13:69.

6: Maghbooli Z, Pasalar P, Keshtkar A, Farzadfar F, Larijani B. Predictive factors of diabetic complications: a possible link between family history of diabetes and diabetic retinopathy. J Diabetes Metab Disord. 2014 May 8;13:55.

7: Mosayebnia M, Shafiee-Ardestani M, Pasalar P, Mashayekhi M, Amanlou M. Diethylentriaminepenta acetic acid glucose conjugates as a cell permeable iron chelator. J Pharmacol Pharmacother. 2014 Jan;5(1):27-32.

 

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