Tissue Engineering

The School of Advanced Technologies in Medicine was established in 2009 as a part of Tehran University of Medical Sciences. The education and research activities of this school are taking place in five departments. In the department of Tissue Engineering and Applied Cell Sciences, we are offering two main programs in Ph.D. degree including “Tissue Engineering” and “Applied Cell Sciences”. Tissue engineering is an emerging field that aims at regeneration of natural tissues and the creation of new tissues using biological cells, biomaterials, biotechnology, and clinical medicine. A commonly applied definition of tissue engineering is "an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole organ". Tissue engineering involves the use of living cells to develop biological substitutes for tissue replacements with the ultimate goal of regeneration and repairing the damaged organs.

Applied Cell Scinces is known as a branch of biological science which is involved in extraction, culture, manipulation and differentiation of cells towards using in treatment of various diseases.

Academic members of this department are involving in multi disciplinary investigations in a broad range of the different scientific fields as follow.

 Design, synthesis and characterization of tissue engineering scaffold made from various biomaterials such as calcium phosphates, bioactive glasses, natural and synthetic polymers.

Stem cell based tissue engineering

Investigation of tissue repair (Bone, Cartilage, Cardiac patch, Skin, Pancreas….) using biomaterials

differentiation and application of various manipulations on the stem cells for treatment of different diseases. 

 Research interests in the Department of Tissue Engineering and Applied Cell Sciences are:

● Neural tissue engineering using mesenchymal stem cells (Endometrial stem cells, Adipose-Derived Stem Cells, stem cells derived from Wharton's Jelly of the umbilical cord, bone marrow stem cells, Induced pluripotent stem cells (iPS) on/in hydrogel scaffold.

● Bone and cartilage tissue engineering using mesenchymal stem cells (Endometrial stem cells, Adipose-Derived Stem Cells, stem cells derived from Wharton's Jelly of the umbilical cord, bone marrow stem cells on polymeric(hydrogel) and polymer/ceramic nanocomposite scaffold.

● Cardiac tissue engineering using mesenchymal stem cells (Endometrial stem cells, Adipose-Derived Stem Cells, stem cells derived from Wharton's Jelly of the umbilical cord, bone marrow stem cells, neonatal rat cardiomyocytes on electroactive polyurethanes membrane.

● Pancreatic tissue engineering using mesenchymal stem cells (Endometrial stem cells, bone marrow stem cells, Induced pluripotent stem cells (iPS)

● Hepatic tissue engineering using mesenchymal stem cells (Endometrial stem cells, Adipose-Derived Stem Cells, stem cells derived from Wharton's Jelly of the umbilical cord, bone marrow stem cells) on….

● Retinal tissue engineering using orbital fat mesenchymal stem cells and collagen hydrogel scaffold

● Gonad tissue engineering using mesenchymal stem cells, endometrial stem cells

● Dental tissue engineering using mesenchymal stem cells human endometrial stem cells on…

● Design and synthesis of various scaffolds for different tissues

● Synthesis of various calcium phosphate materials (Hydroxyapatite, Tricalcium phosphate …) and bioactive glasses intended for biomedical application.

       Curriculum Tissue Engineering (Ph.D.)